Anorectal Malignant Melanoma: Morphologic and Immunohistochemical Features
نویسندگان
چکیده
منابع مشابه
Anorectal malignant melanoma: morphologic and immunohistochemical features.
We reviewed 17 cases of primary anorectal malignant melanoma. Morphologic features evaluated included junctional change, pigmentation, morphology, and mitotic rate. Immunohistochemical stains were performed for/with S-100 protein, HMB-45, MelanA, tyrosinase, vimentin, KIT, and pankeratin. Morphologic subtypes were as follows: epithelioid, 12 cases; spindle cell, 7 cases; lymphoma-like, 10 cases...
متن کاملThe clinical features and optimal treatment of anorectal malignant melanoma
Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of ...
متن کاملIntrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features
Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...
متن کاملMorphologic and immunohistochemical features of breast nevi.
A large number of publications recognize that there are melanocytic lesions with microscopic features similar to melanoma, related to their location. Those locations are represented by the ear, the milk lines (axillary, breast, periumbilical and inguinal regions), palms, soles, and flexural regions. Starting from Rongioletti F et al. study in 2004, we measured 10 histological parameters on 96 n...
متن کاملAmelanotic Anorectal Malignant Melanoma: Case Report with Immunohistochemical Study and Literature Review
Epithelioid cell tumors presenting in the gastrointestinal tract are uncommon, but when they arise, arriving at a correct diagnosis is important. We report a case of anal malignant melanoma in an 82-year-old man who microscopically showed an epithelioid malignant tumor simulating a gastrointestinal stromal tumor. C-kit stain and Melan-A were diffusely and strongly positive, while HMB-45 was foc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2006
ISSN: 0002-9173
DOI: 10.1309/dvwl-tv8f-fkc3-l80h